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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL283037
Molecular formula	C22H21F3N2O5
IUPAC name	2-[4-(1,3-benzodioxol-5-ylmethyl)-2-[(3-methoxyphenyl)methyl]-5-(trifluoromethyl)pyrazol-3-yl]oxyethanol
Molecular weight	450.414
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	4.1
Synonyms	2-[1-(3-Methoxybenzyl)-3-(trifluoromethyl)-4-(1,3-benzodioxole-5-ylmethyl)-1H-pyrazole-5-yloxy]ethanol BDBM50089718 SCHEMBL9055213 2-[4-Benzo[1,3]dioxol-5-ylmethyl-2-(3-methoxy-benzyl)-5-trifluoromethyl-2H-pyrazol-3-yloxy]-ethanol
Inchi Key	CTVCWMDGTLMFFO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H21F3N2O5/c1-29-16-4-2-3-15(9-16)12-27-21(30-8-7-28)17(20(26-27)22(23,24)25)10-14-5-6-18-19(11-14)32-13-31-18/h2-6,9,11,28H,7-8,10,12-13H2,1H3
PubChem CID	44277130
ChEMBL	CHEMBL283037
IUPHAR	N/A
BindingDB	50089718
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
50456	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
50457	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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