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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2147920
Molecular formula	C25H23F3N2O2
IUPAC name	(1R,14S,15R)-25-methyl-9-(trifluoromethyl)-4,25-diazahexacyclo[13.7.3.01,14.03,12.05,10.017,22]pentacosa-3,5,7,9,11,17(22),18,20-octaene-14,20-diol
Molecular weight	440.466
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.3
Synonyms	CHEMBL2220032 BDBM50391607
Inchi Key	CQJGLYPYRSUYPN-WXFUMESZSA-N
Inchi ID	InChI=1S/C25H23F3N2O2/c1-30-8-7-23-13-21-15(9-17-18(25(26,27)28)3-2-4-20(17)29-21)12-24(23,32)22(30)10-14-5-6-16(31)11-19(14)23/h2-6,9,11,22,31-32H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1
PubChem CID	71456465
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50391607
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
48130	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
48129	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
48128	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398

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