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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL428909
Molecular formula	C18H16N4O2S
IUPAC name	13-(dimethylamino)-5-(4-methoxyphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight	352.412
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.2
Synonyms	CBMicro_043946 MolPort-000-756-937 9-dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3'',2'':4,5]thieno[3,2-d]pyrimidin-4-one SMR000070555 BDBM50224397 MCULE-2396629148 ZINC978708 CHEBI:112408 Oprea1_169330 AC1LNTGL cid_1208332 SR-01000225835 BIM-0044083.P001 MLS000061301 9-(dimethylamino)-3-(4-methoxyphenyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one SCHEMBL8236262 AH-262/36083018 HMS2347B14 SR-01000225835-1 [ Show all ]
Inchi Key	COQPVKMATNFNLG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H16N4O2S/c1-21(2)13-8-9-19-17-14(13)15-16(25-17)18(23)22(10-20-15)11-4-6-12(24-3)7-5-11/h4-10H,1-3H3
PubChem CID	1208332
ChEMBL	CHEMBL428909
IUPHAR	N/A
BindingDB	50224397
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
46908	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
46906	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
46907	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
46909	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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