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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL302225
Molecular formula	C14H16N4S
IUPAC name	8-(4-methylpiperazin-1-yl)-5-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaene
Molecular weight	272.37
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.1
Synonyms	BDBM50407774 SCHEMBL7306195 5-(4-Methyl-1-piperazinyl)pyrrolo[1,2-a]thieno[2,3-e]pyrazine
Inchi Key	CMBPNOCCPKFOHS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H16N4S/c1-16-6-8-17(9-7-16)13-11-3-2-5-18(11)12-4-10-19-14(12)15-13/h2-5,10H,6-9H2,1H3
PubChem CID	10826076
ChEMBL	CHEMBL302225
IUPHAR	N/A
BindingDB	50407774
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
45202	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
45203	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
45204	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
45205	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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