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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL605307
Molecular formula	C22H28N4O
IUPAC name	1-[5-(3-tert-butylphenyl)-1-(3-methoxyphenyl)-1,2,4-triazol-3-yl]-N,N-dimethylmethanamine
Molecular weight	364.493
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.8
Synonyms	BDBM50304081 SCHEMBL9881192 (5-(3-tert-Butylphenyl)-1-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
Inchi Key	CFDMEKQECKVSMF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28N4O/c1-22(2,3)17-10-7-9-16(13-17)21-23-20(15-25(4)5)24-26(21)18-11-8-12-19(14-18)27-6/h7-14H,15H2,1-6H3
PubChem CID	46226492
ChEMBL	CHEMBL605307
IUPHAR	N/A
BindingDB	50304081
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
40535	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
40533	Kappa-type opioid receptor	P34975	Oprk1	Rattus norvegicus (Rat)	380
40534	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398

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