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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	152121-47-6
Molecular formula	C21H16FN3OS
IUPAC name	4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine
Molecular weight	377.437
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.2
Synonyms	GTPL5269 HMS3403H05 2Z5A7553WW KB-34197 4-(5-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-4-yl)pyridine MolPort-020-313-396 652162-77-1 PB-203580, (R)- AKOS015994568 QC-11773 BDBM192501 RWJ-64809\|\|\|PB-203580\|\|\|4-[4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine BRD-A37704979-001-02-4 SB-203580, (S)- CDMGBJANTYXAIV-UHFFFAOYSA-N SR-01000597367 CTK8E9223 TRA0064819 US9187470, 104 (SB203580) HMS3229O04 I14-10276 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazol LS-186976 4-[5-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-3H-imidazol-4-yl]pyridine NCGC00025035-03 AB0033710 Pyridine, 4-(4-(4-fluorophenyl)-2-(5-((S)-methylsulfinyl)phenyl)-1H-imidazol-4-yl)- AOB6367 RWJ 64809 Bio1_000745 SB 203580 BSPBio_001104 SB203580,RWJ 64809,PB 203580 SYN1074 DTXSID2040577 ZX-AFC000489 HMS3244J15 J-513573 4-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-5- MLS006010840 4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine NCGC00381704-12 AK-51369 Pyridine, 4-[5-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-yl]- BCPP000074 RWJ-64809, (S)- BIRB-203580, (S)- SB-203580 cc-50 SCHEMBL95208 CS-0140 Tocris-1202 FT-0674525 HMS1792H05 HMS3654M15 4-(4-(4-Fluorophenyl)-2-(4-(methylsulfinyl)-phenyl)-1H-imidazol-5-yl)pyridine Kinome_2521 4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine NCGC00025035-01 896734-47-7 PB-203580, (S)- AM81234 RS0055 BDBM50045333 S-7702 BRD-A37704979-003-01-2 SB16633 CF-031 SR-01000597367-1 D0F8DL UNII-2Z5A7553WW WS78QR6DSV HMS3244I15 121S476 InSolution™ SB 203580 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole LS-187618 4-[5-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-3H-imidazol-4-yl]pyridine NCGC00025035-04 ABP000230 Pyridine, 4-(5-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-4-yl)- AX8150875 RWJ 64809, PB 203580, 152121-47-6 Bio1_001234 SB 203580 & Z-100 C21H16FN3OS SB203580/SB-203580 CHEMBL10 TC-063053 ES-0013 GK9716 HMS3267B07 1pme K00038 4-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-5-(4-pyridyl)-1H-imidazole MolPort-000-006-291 4CA-1136 PB 203580 AKOS005145971 Pyridine, 4-[5-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-yl]- & Z-100 BDBM13336 RWJ-64809; BIS0733 SB-203580, (R)- CCG-206878 SMR004701767 CTK7C0221 Tocris-1402 HMS1990H05 HY-10256 4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine KS-000018EO 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine NCGC00025035-02 A15256 Pyridine, 4-(4-(4-fluorophenyl)-2-(5-((R)-methylsulfinyl)phenyl)-1H-imidazol-4-yl)- ANW-72176 RTC-063053 Bio1_000256 s1076 BS0218 SB203580 CHEBI:90705 SW218141-2 DB-026130 UNII-WS78QR6DSV X7403 HMS3244I16 J-008891 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole MFCD00922198 4-{4-(4-fluorophenyl)-2-[4-(methanesulfinyl)phenyl]-1H-imidazol-5-yl}pyridine NCGC00025035-05 AC1L41YG Pyridine, 4-[4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]- BCP01763 RWJ-64809, (R)- BIRB-203580, (R)- SB 203580, solid, >=98% (HPLC) CBiol_001970 SC-27890 cid_176155 TC-160921 EX-A134 [ Show all ]
Inchi Key	CDMGBJANTYXAIV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)
PubChem CID	176155
ChEMBL	CHEMBL10
IUPHAR	N/A
BindingDB	13336
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
443251	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
39427	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
39430	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
39428	Glucagon receptor	P47871	GCGR	Homo sapiens (Human)	477
39426	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
39429	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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