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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	H-SER-PHE-LEU-LEU-ARG-NH2
Molecular formula	C30H51N9O6
IUPAC name	(2S)-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Molecular weight	633.795
Hydrogen bond acceptor	8
Hydrogen bond donor	9
XlogP	-0.5
Synonyms	P5-NH2 (S)-2-((S)-2-((S)-2-amino-3-hydroxypropanamido)-3-phenylpropanamido)-N-((S)-1-((S)-1-amino-5-guanidino-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-4-methylpentanamide BDBM85516 THROMBIN RECEPTOR AGONIST,AMIDE (SFLLR - NH2) 1N-[1-[4-amino(imino)methylamino-1-carbamoyl-(1S)-butylcarbamoyl]-3-methyl-(1S)-butyl]-2-[1-[1-amino-2-hydroxy-(1S)-ethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanamide CHEMBL115543 AKOS030525614 Ser-Phe-Leu-Leu-Arg-NH2 (S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid [(S)-1-((S)-1-carbamoyl-4-guanidino-butylcarbamoyl)-3-methyl-butyl]-amide CAS_141923-41-3 ZINC27076581 (S)-2-((S)-2-((S)-2-Amino-3-hydroxyPropanamido)-3-phenylPropanamido)-N-((S)-1-(((S)-1-amino-5-guanidino-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)-4-methylpentanamide BDBM50031381 SFLLR-NH2 141923-41-3 [ Show all ]
Inchi Key	CDBPTZOOUNAWQA-LSBAASHUSA-N
Inchi ID	InChI=1S/C30H51N9O6/c1-17(2)13-22(27(43)36-21(25(32)41)11-8-12-35-30(33)34)38-28(44)23(14-18(3)4)39-29(45)24(37-26(42)20(31)16-40)15-19-9-6-5-7-10-19/h5-7,9-10,17-18,20-24,40H,8,11-16,31H2,1-4H3,(H2,32,41)(H,36,43)(H,37,42)(H,38,44)(H,39,45)(H4,33,34,35)/t20-,21-,22-,23-,24-/m0/s1
PubChem CID	9809471
ChEMBL	CHEMBL115543
IUPHAR	N/A
BindingDB	85516, 50031381
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
39134	Proteinase-activated receptor 1	P25116	F2R	Homo sapiens (Human)	425
39133	Proteinase-activated receptor 2	Q63645	F2rl1	Rattus norvegicus (Rat)	397

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