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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL238180
Molecular formula	C22H25N3O
IUPAC name	N-(3-aminopropyl)-N-(1,2,3,4-tetrahydronaphthalen-2-yl)-1H-indole-3-carboxamide
Molecular weight	347.462
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	3.3
Synonyms	BDBM50217768 N-(3-aminopropyl)-N-(1,2,3,4-tetrahydronaphthalen-2-yl)-1H-indole-3-carboxamide
Inchi Key	CBRMUBMTRMALEN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25N3O/c23-12-5-13-25(18-11-10-16-6-1-2-7-17(16)14-18)22(26)20-15-24-21-9-4-3-8-19(20)21/h1-4,6-9,15,18,24H,5,10-14,23H2
PubChem CID	10269187
ChEMBL	CHEMBL238180
IUPHAR	N/A
BindingDB	50217768
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
38151	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
38153	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
38150	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325
38152	Melanocyte-stimulating hormone receptor	Q01727	Mc1r	Mus musculus (Mouse)	315

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