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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL123301
Molecular formula	C33H38N4O2
IUPAC name	5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]-N-[[4-[(pyrimidin-2-ylamino)methyl]phenyl]methyl]furan-2-carboxamide
Molecular weight	522.693
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	7.6
Synonyms	BDBM50121473 N-[4-(2-Pyrimidinylaminomethyl)benzyl]-5-(1,1,4,4,7-pentamethyltetralin-6-ylmethyl)furan-2-carboxamide 5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-ylmethyl)-furan-2-carboxylic acid 4-(pyrimidin-2-ylaminomethyl)-benzylamide
Inchi Key	BWHICKVEBDPGMZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H38N4O2/c1-22-17-27-28(33(4,5)14-13-32(27,2)3)19-25(22)18-26-11-12-29(39-26)30(38)36-20-23-7-9-24(10-8-23)21-37-31-34-15-6-16-35-31/h6-12,15-17,19H,13-14,18,20-21H2,1-5H3,(H,36,38)(H,34,35,37)
PubChem CID	21045834
ChEMBL	CHEMBL123301
IUPHAR	N/A
BindingDB	50121473
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
34440	Gonadotropin-releasing hormone receptor	P30969	Gnrhr	Rattus norvegicus (Rat)	327
34441	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328

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