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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17418575
Molecular formula	C34H41FN2O5
IUPAC name	(3S)-3-cyclopropyl-3-[3-[[5-(2-fluoro-5-methoxyphenyl)-6-(3,3,5,5-tetramethylcyclohexyl)oxypyrazin-2-yl]methoxy]phenyl]propanoic acid
Molecular weight	576.709
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	7.5
Synonyms	BDBM168161 US9688642, 24 (3S)-3-Cyclopropyl-3-(3-((5-(2-fluoro-5-methoxyphenyl)-6-(3,3,5,5-tetramethylcyclohexyloxy)pyrazin-2-yl)methoxy)phenyl)propanoic acid BUZDQZLYIICDDD-MHZLTWQESA-N
Inchi Key	BUZDQZLYIICDDD-MHZLTWQESA-N
Inchi ID	InChI=1S/C34H41FN2O5/c1-33(2)16-26(17-34(3,4)20-33)42-32-31(28-14-24(40-5)11-12-29(28)35)36-18-23(37-32)19-41-25-8-6-7-22(13-25)27(15-30(38)39)21-9-10-21/h6-8,11-14,18,21,26-27H,9-10,15-17,19-20H2,1-5H3,(H,38,39)/t27-/m0/s1
PubChem CID	118645378
ChEMBL	N/A
IUPHAR	N/A
BindingDB	168161
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
558295	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300
558296	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300

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