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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-[4-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]morpholine
Molecular formula	C14H23N5O
IUPAC name	4-[4-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]morpholine
Molecular weight	277.372
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	1.0
Synonyms	AKOS000549556 MCULE-5478514203 CHEBI:109819 SMR000012255 HMS2179G22 BAS 03357967 MLS000026829 2-(4-Morpholinyl)-4-methyl-6-(4-methyl-1-piperazinyl)pyrimidine STK537218 AC1LDH1N J3.528.915A Cambridge id 6742137 MolPort-001-848-275 4-[4-Methyl-6-(4-methyl-piperazin-1-yl)-pyrimidin-2-yl]-morpholine CHEMBL1381010 ZINC73496 [ Show all ]
Inchi Key	BMBIEKJDTGAZCY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H23N5O/c1-12-11-13(18-5-3-17(2)4-6-18)16-14(15-12)19-7-9-20-10-8-19/h11H,3-10H2,1-2H3
PubChem CID	647957
ChEMBL	CHEMBL1381010
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
522378	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
522379	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
27276	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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