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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3326359
Molecular formula	C22H25NO5
IUPAC name	(1S,3S,4S,6R,7S)-3,6-bis(3-methoxyphenyl)-3,6-dimethyl-2,5,8-trioxa-10-azatricyclo[5.2.1.04,10]decane
Molecular weight	383.444
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.0
Synonyms	(2S,4R)-2,2abeta,4,4abeta,6,6abeta-Hexahydro-2,4-bis(3-methoxyphenyl)-2,4-dimethyl-1,3,5-trioxa-6b-azacyclopenta[cd]pentalene BDBM50101310
Inchi Key	BISYCXYJFMIOEX-KGWSWXIGSA-N
Inchi ID	InChI=1S/C22H25NO5/c1-21(14-7-5-9-16(11-14)24-3)19-23-18(13-26-19)27-22(2,20(23)28-21)15-8-6-10-17(12-15)25-4/h5-12,18-20H,13H2,1-4H3/t18-,19-,20-,21+,22-/m0/s1
PubChem CID	102265762
ChEMBL	CHEMBL3326359
IUPHAR	N/A
BindingDB	50101310
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
442637	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
442635	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
442636	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398

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