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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1O0HXG
Molecular formula	C18H18FN7O
IUPAC name	2-[(E)-[[4-(dimethylamino)-6-(4-fluoroanilino)-1,3,5-triazin-2-yl]hydrazinylidene]methyl]phenol
Molecular weight	367.388
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	4.0
Synonyms	2-hydroxybenzaldehyde 1-[4-(dimethylamino)-6-(4-fluoroanilino)-1,3,5-triazin-2-yl]hydrazone AKOS001713502 A1299/0059068 MCULE-8041951779 AC1O43FH 2-[(E)-(2-{4-(dimethylamino)-6-[(4-fluorophenyl)amino]-1,3,5-triazin-2-yl}hydrazinylidene)methyl]phenol A1399/0062516 MolPort-002-698-226 (6Z)-6-[[2-[4-(dimethylamino)-6-(4-fluoroanilino)-1,3,5-triazin-2-yl]hydrazinyl]methylidene]cyclohexa-2,4-dien-1-one AC1OB41T 6-[[2-[4-(dimethylamino)-6-(4-fluoroanilino)-1,3,5-triazin-2-yl]hydrazinyl]methylidene]cyclohexa-2,4-dien-1-one CHEMBL3193805 STK755093 [ Show all ]
Inchi Key	AXZWNDUUVWCUGC-RGVLZGJSSA-N
Inchi ID	InChI=1S/C18H18FN7O/c1-26(2)18-23-16(21-14-9-7-13(19)8-10-14)22-17(24-18)25-20-11-12-5-3-4-6-15(12)27/h3-11,27H,1-2H3,(H2,21,22,23,24,25)/b20-11+
PubChem CID	135460597
ChEMBL	CHEMBL3193805
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557765	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
557763	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
557764	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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