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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL497557
Molecular formula	C25H25ClF3N5O
IUPAC name	N-[1-[6-(3-chloropyridin-4-yl)-5-[4-(trifluoromethyl)phenyl]pyrazin-2-yl]piperidin-4-yl]-2-methylpropanamide
Molecular weight	503.954
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	4.9
Synonyms	BDBM50260806 N-(1-(6-(3-chloropyridin-4-yl)-5-(4-(trifluoromethyl)phenyl)pyrazin-2-yl)piperidin-4-yl)isobutyramide N-{1-[6-(3-Chloro-pyridin-4-yl)-5-(4-trifluoromethyl-phenyl)-pyrazin-2-yl]-piperidin-4-yl}-isobutyramide AWWGUVKCDIOPIQ-UHFFFAOYSA-N SCHEMBL4696771
Inchi Key	AWWGUVKCDIOPIQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H25ClF3N5O/c1-15(2)24(35)32-18-8-11-34(12-9-18)21-14-31-22(16-3-5-17(6-4-16)25(27,28)29)23(33-21)19-7-10-30-13-20(19)26/h3-7,10,13-15,18H,8-9,11-12H2,1-2H3,(H,32,35)
PubChem CID	24857903
ChEMBL	CHEMBL497557
IUPHAR	N/A
BindingDB	50260806
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16415	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
16417	Cannabinoid receptor 1	P20272	Cnr1	Rattus norvegicus (Rat)	473
16416	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360

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