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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL300330
Molecular formula	C7H12N2O4
IUPAC name	(2R,4R)-4-amino-1-methylpyrrolidine-2,4-dicarboxylic acid
Molecular weight	188.183
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-6.0
Synonyms	AKOS027402606 (2R,4R)-4-Amino-1-methyl-pyrrolidine-2,4-dicarboxylic acid 213619-98-8 SCHEMBL14278713 BDBM50071164 (2R,4R)-4-amino-1-methylpyrrolidine-2,4-dicarboxylic acid CTK1A0056 ZINC29571185 2,4-Pyrrolidinedicarboxylicacid, 4-amino-1-methyl-, (2R,4R)- DTXSID10658238 [ Show all ]
Inchi Key	AWGRHEDNWXKCFJ-CLZZGJSISA-N
Inchi ID	InChI=1S/C7H12N2O4/c1-9-3-7(8,6(12)13)2-4(9)5(10)11/h4H,2-3,8H2,1H3,(H,10,11)(H,12,13)/t4-,7-/m1/s1
PubChem CID	44302818
ChEMBL	CHEMBL300330
IUPHAR	N/A
BindingDB	50071164
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16006	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
16005	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
16007	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
16004	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
16003	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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