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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	635318-11-5
Molecular formula	C7H9NO6S
IUPAC name	(1R,4S,5S,6S)-4-amino-2,2-dioxo-2lambda6-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
Molecular weight	235.21
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	-4.8
Synonyms	LY2140023/LY404039/ UNII-531QUG7P9E (-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide 318L115 AN-3553 C12H18N2O7S2 CTK2F1748 MolPort-009-679-373 X7608 (1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide BC252688 CHEBI:94640 HY-50906 SB19521 1R,4S,5S,6S)-4-AMino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide ABP000193 BDBM50202407 CM11052 LY-404039 LY404039 W-5502 (1R,4S,5S,6S)-4-amino-2,2-dioxo-2$l^{6}-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid API0005879 C21577 DTXSID40212943 NCGC00346612-01 ZINC13910898 (1R,4S,5S,6S)-4-[[(2S)-2-Amino-4-(methylthio)-1-oxobutyl]amino]-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide 635318-11-5 , C7H9NO6S , LY404039 , LY-404039 , LY 2140023 BCP9000869 KB-78254 LY2140023 (LY404039) SCHEMBL1088010 2-Thiabicyclo[3.1.0]hexane-4,6-dicarboxylicacid, 4-amino-, 2,2-dioxide, (1R,4S,5S,6S)- AKOS030526171 BRD-K49519144-001-01-2 CS-1345 MFCD11974011 X6978 (1R,4S,5S,6S)-4-amino-2,2-dioxo-26-thia-bicyclo[3.1.0]hexane-4,6-dicarboxylic acid 531QUG7P9E AS-19328 C7H9NO6S EX-A2094 s6001 (1S,2S,5R,6S)-2-amino-4,4-dioxo-4$l^{6}-thiabicyclo[3.1.0]hexane-2,6-dicarboxylic acid A8747 BCPP000181 CHEMBL375611 LY 404039 [ Show all ]
Inchi Key	AVDUGNCTZRCAHH-MDASVERJSA-N
Inchi ID	InChI=1S/C7H9NO6S/c8-7(6(11)12)1-15(13,14)4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2-,3-,4+,7+/m1/s1
PubChem CID	9834591
ChEMBL	CHEMBL375611
IUPHAR	N/A
BindingDB	50202407
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15208	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
15207	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
15206	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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