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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL66388
Molecular formula	C21H29N3
IUPAC name	N-(3-pyrrolidin-1-ylpropyl)-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine
Molecular weight	323.484
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.8
Synonyms	(3-Pyrrolidin-1-yl-propyl)-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)-amine BDBM50129253 11-(3-Pyrrolizinopropylamino)-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline
Inchi Key	AVBATPOOKQCBKS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H29N3/c1-2-9-17-19(11-3-1)23-20-12-5-4-10-18(20)21(17)22-13-8-16-24-14-6-7-15-24/h4-5,10,12H,1-3,6-9,11,13-16H2,(H,22,23)
PubChem CID	9818650
ChEMBL	CHEMBL66388
IUPHAR	N/A
BindingDB	50129253
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15143	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
15145	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
15144	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
15146	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445

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