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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL526472
Molecular formula	C23H22ClNO3S
IUPAC name	5-[(7S)-7-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydronaphthalen-2-yl]thiophene-2-carboxylic acid
Molecular weight	427.943
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.6
Synonyms	5-((7S)-7-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino}-5,6,7,8-tetrahydro-2-naphthalenyl)-2-thiophenecarboxylic Acid BDBM50272879
Inchi Key	ASLXIOZFLLFQLE-PMACEKPBSA-N
Inchi ID	InChI=1S/C23H22ClNO3S/c24-18-3-1-2-15(11-18)20(26)13-25-19-7-6-14-4-5-16(10-17(14)12-19)21-8-9-22(29-21)23(27)28/h1-5,8-11,19-20,25-26H,6-7,12-13H2,(H,27,28)/t19-,20-/m0/s1
PubChem CID	24950409
ChEMBL	CHEMBL526472
IUPHAR	N/A
BindingDB	50272879
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13272	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
13271	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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