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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	Bimatoprost
Molecular formula	C25H37NO4
IUPAC name	(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
Molecular weight	415.574
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	2.8
Synonyms	BDBM220120 CHEBI:51230 GTPL1958 Lumigan (TN) SMR000058996 (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide 267244-98-4 AGN 192024 Bimatoprost (JAN/USAN/INN) D02724 I06-1277 MolPort-006-167-657 UNII-QXS94885MZ (5z)-7-{(1r,2r,3r,5s)-3,5-Dihydroxy-2-[(1e,3s)-3-Hydroxy-5-Phenylpent-1-Enyl]cyclopentyl}-N-Ethylhept-5-Enamide 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ETHYL AMIDE 5-Heptenamide, 7-(3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (1R-1(alpha(Z),2beta(1E,3S)3alpha,5alpha))- AKOS015995566 AQOKCDNYWBIDND-FTOWTWDKSA-N Bimatoprost/Lumigan DB00905 LS-181817 RP17728 (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)-N-ethylhept-5-enamide ABP000616 Bimataprost [USAN:INN:BAN] CHEMBL1200963 HY-B0191 M052 SR-01000942224 (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept-5-enamide 155206-00-1 5-Heptenamide, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (5Z)- AGN-192024 AM84507 Bimatoprost (topical, alopecia) D0Q2XF Latisse NCGC00181745-01 US9271961, Bimatoprost (E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide 17-Phenyl-tri-norprostaglandin F2alpha-ethyl amide 5-Heptenamide,7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ehtyl-,(5Z) AS-35082 bimatoprostum EX-A1769 Lumigan SCHEMBL24425 (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenyl-pent-1-enyl]cyclopentyl]-N-ethyl-hept-5-enamide 206B001 AC1NSJUW CS-2085 I06-1275 MLS006010039 SR-01000942224-1 (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide 15M 5-Heptenamide, 7-(3,5-dihydroxy-2-(3-hydrdoxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (1R-(1alpha(Z),2beta(1E,3S),3alpha,5alpha))- AK173142 AN-5283 Bimatoprost [USAN:INN:BAN:JAN] Latisse (TN) QXS94885MZ ZINC4474405 (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide 17-Phenyl-tri-norprostaglandin F2alpha-ethyl amide, >=95%, solid AB0015029 [ Show all ]
Inchi Key	AQOKCDNYWBIDND-FTOWTWDKSA-N
Inchi ID	InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1
PubChem CID	5311027
ChEMBL	N/A
IUPHAR	1958
BindingDB	N/A
DrugBank	DB00905
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11959	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
11960	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
11958	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359

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