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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Molecular formula	C9H8N6OS
IUPAC name	2-(furan-2-yl)-5-methylsulfanyl-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Molecular weight	248.264
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	1.1
Synonyms	2-(2-Furyl)-5-(methylthio)[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine 7-amino-2-(2-furyl)-5-methylthio-[1,2,4]triazolo[1,5-a][1,3,5]triazine APSHQFCMMKRIFB-UHFFFAOYSA-N CHEMBL1090123 7-amino-2-(2-furyl)-5-methylthio[1,2,4]triazolo[1,5-a][1,3,5]triazine 139181-27-4 BDBM50315604 SCHEMBL9264847 AKOS027461136 [ Show all ]
Inchi Key	APSHQFCMMKRIFB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C9H8N6OS/c1-17-9-12-7(10)15-8(13-9)11-6(14-15)5-3-2-4-16-5/h2-4H,1H3,(H2,10,11,12,13,14)
PubChem CID	11776764
ChEMBL	CHEMBL1090123
IUPHAR	N/A
BindingDB	50315604
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11294	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
11295	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
11293	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
442148	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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