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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1775175
Molecular formula	C22H25N5O6S
IUPAC name	oxolan-3-yl 4-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxypiperidine-1-carboxylate
Molecular weight	487.531
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	1.9
Synonyms	BDBM50343438 142887-EP2287165A2 SCHEMBL389554 4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy]-piperidine-1-carboxylic acid tetrahydro-furan-3-yl ester 142887-EP2287166A2 tetrahydrofuran-3-yl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate 142887-EP2292620A2 [ Show all ]
Inchi Key	AOGFVKCXWUDFAJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25N5O6S/c1-34(29,30)18-4-2-15(3-5-18)27-20-19(12-25-27)21(24-14-23-20)32-16-6-9-26(10-7-16)22(28)33-17-8-11-31-13-17/h2-5,12,14,16-17H,6-11,13H2,1H3
PubChem CID	21897616
ChEMBL	CHEMBL1775175
IUPHAR	N/A
BindingDB	50343438
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10216	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468
10217	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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