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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL432170
Molecular formula	C29H40F3N5O
IUPAC name	(4,6-dimethylpyrimidin-5-yl)-[4-methyl-4-[(3S)-3-methyl-4-[(1S)-1-[4-(trifluoromethyl)phenyl]butyl]piperazin-1-yl]piperidin-1-yl]methanone
Molecular weight	531.668
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	5.1
Synonyms	(4,6-dimethylpyrimidin-5-yl)-[4-methyl-4-[(3S)-3-methyl-4-[(1S)-1-[4-(trifluoromethyl)phenyl]butyl]piperazin-1-yl]piperidin-1-yl]methanone AC1MHPZH (4,6-Dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-butyl]-piperazin-1-yl}-piperidin-1-yl)-methanone 1-(4,6-Dimethyl-pyrimidin-5-yl)-1-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-butyl]-piperazin-1-yl}-piperidin-1-yl)-methanone BDBM50145684 (4,6-dimethylpyrimidin-5-yl)-[4-methyl-4-[(3S)-3-methyl-4-[(1S)-1-[4-(trifluoromethyl)phenyl]butyl]piperazin-1-yl]-1-piperidyl]methanone [ Show all ]
Inchi Key	AKVBPIBFLBXBAR-CPJSRVTESA-N
Inchi ID	InChI=1S/C29H40F3N5O/c1-6-7-25(23-8-10-24(11-9-23)29(30,31)32)37-17-16-36(18-20(37)2)28(5)12-14-35(15-13-28)27(38)26-21(3)33-19-34-22(26)4/h8-11,19-20,25H,6-7,12-18H2,1-5H3/t20-,25-/m0/s1
PubChem CID	3009353
ChEMBL	CHEMBL432170
IUPHAR	N/A
BindingDB	50145684
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7924	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352
7923	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
7922	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
7925	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590

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