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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL132408
Molecular formula	C27H24N8O
IUPAC name	[5-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]indol-1-yl]-[2-(2H-tetrazol-5-yl)phenyl]methanone
Molecular weight	476.544
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.7
Synonyms	AFOQZUNUKPCIHO-UHFFFAOYSA-N 3-[N-(2-tetrazol-5-yl-benzoyl)-5-indolyl]methyl-5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]pyridine [5-(2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-4-ylmethyl)-indol-1-yl]-[2-(1H-tetrazol-5-yl)-phenyl]-methanone BDBM50043436 L007654 SCHEMBL9662040 [ Show all ]
Inchi Key	AFOQZUNUKPCIHO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H24N8O/c1-4-23-29-24-16(2)13-17(3)28-26(24)35(23)15-18-9-10-22-19(14-18)11-12-34(22)27(36)21-8-6-5-7-20(21)25-30-32-33-31-25/h5-14H,4,15H2,1-3H3,(H,30,31,32,33)
PubChem CID	10367704
ChEMBL	CHEMBL132408
IUPHAR	N/A
BindingDB	50043436
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4361	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
4360	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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