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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL235798
Molecular formula	C26H29N5O
IUPAC name	N-[3-(diaminomethylideneamino)propyl]-3-(1H-indol-3-yl)-N-(naphthalen-2-ylmethyl)propanamide
Molecular weight	427.552
Hydrogen bond acceptor	2
Hydrogen bond donor	3
XlogP	3.3
Synonyms	SCHEMBL7866512 BDBM50217737 N-(3-Guanidino-propyl)-3-(1H-indol-3-yl)-N-naphthalen-2-ylmethyl-propionamide
Inchi Key	AESDVUXZXPNTFN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H29N5O/c27-26(28)29-14-5-15-31(18-19-10-11-20-6-1-2-7-21(20)16-19)25(32)13-12-22-17-30-24-9-4-3-8-23(22)24/h1-4,6-11,16-17,30H,5,12-15,18H2,(H4,27,28,29)
PubChem CID	23653113
ChEMBL	CHEMBL235798
IUPHAR	N/A
BindingDB	50217737
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3807	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
3806	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
3808	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325
3805	Melanocyte-stimulating hormone receptor	Q01727	Mc1r	Mus musculus (Mouse)	315

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