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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000207614
Molecular formula	C14H14N2O2
IUPAC name	(E)-3-(1,3-dimethylpyrazol-4-yl)-1-(4-hydroxyphenyl)prop-2-en-1-one
Molecular weight	242.278
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.0
Synonyms	AKOS001677066 REGID_for_CID_5865241 SR-01000150408-1 CHEMBL1520538 (E)-3-(1,3-dimethylpyrazol-4-yl)-1-(4-hydroxyphenyl)prop-2-en-1-one MLS000585833 BDBM67594 STK046180 (2E)-3-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(4-hydroxyphenyl)prop-2-en-1-one cid_5865241 AC1NYT2T MolPort-001-649-655 SR-01000150408 ZINC4349828 (E)-3-(1,3-dimethyl-4-pyrazolyl)-1-(4-hydroxyphenyl)-2-propen-1-one HMS2570P16 [ Show all ]
Inchi Key	ABAWOOLKLLGUCV-VMPITWQZSA-N
Inchi ID	InChI=1S/C14H14N2O2/c1-10-12(9-16(2)15-10)5-8-14(18)11-3-6-13(17)7-4-11/h3-9,17H,1-2H3/b8-5+
PubChem CID	5865241
ChEMBL	CHEMBL1520538
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
717	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463030	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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