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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000127857
Molecular formula	C21H18N2O2
IUPAC name	4-methyl-N-[(4-methylphenyl)methyl]furo[3,2-c]quinoline-2-carboxamide
Molecular weight	330.387
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.5
Synonyms	HMS2241I23 CHEBI:123420 ChemDiv2_006725 4-methyl-N-[(4-methylphenyl)methyl]furo[3,2-c]quinoline-2-carboxamide IDI1_005440 HMS1388B15 AC1O7SVM MLS000522590 CHEMBL1301232 [ Show all ]
Inchi Key	AASCFXUFOVMIDS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H18N2O2/c1-13-7-9-15(10-8-13)12-22-21(24)19-11-17-14(2)23-18-6-4-3-5-16(18)20(17)25-19/h3-11H,12H2,1-2H3,(H,22,24)
PubChem CID	6619633
ChEMBL	CHEMBL1301232
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
483	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
484	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
463013	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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