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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-(3,4-Dihydro-1H-isoquinolin-2-yl)-8-methoxy-5H-pyrimido[5,4-b]indole
Molecular formula	C20H18N4O
IUPAC name	4-(3,4-dihydro-1H-isoquinolin-2-yl)-8-methoxy-5H-pyrimido[5,4-b]indole
Molecular weight	330.391
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.7
Synonyms	AC1LIGWY SMR000434440 CHEMBL1533104 4-(3,4-dihydroisoquinolin-2(1H)-yl)-8-methoxy-5H-pyrimido[5,4-b]indole MLS000769793 AKOS005480921 STK554179 HMS2795K04 840471-85-4 MolPort-002-595-257 ZINC522518 MCULE-1026651811 [ Show all ]
Inchi Key	AAOZUMUCPQPFAA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18N4O/c1-25-15-6-7-17-16(10-15)18-19(23-17)20(22-12-21-18)24-9-8-13-4-2-3-5-14(13)11-24/h2-7,10,12,23H,8-9,11H2,1H3
PubChem CID	931001
ChEMBL	CHEMBL1533104
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
418	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
419	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
463007	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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