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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1MR1M1
Molecular formula	C25H24FN5O2
IUPAC name	N-cyclopentyl-7-[(4-fluorophenyl)methyl]-6-imino-11-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide
Molecular weight	445.498
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.7
Synonyms	MLS001139211 ZINC101111164 AKOS005182111 N-cyclopentyl{1-[(4-fluorophenyl)methyl]-2-imino-10-methyl-5-oxo(1,6-dihydropy ridino[2,3-d]pyridino[1,2-a]pyrimidin-3-yl)}carboxamide HMS2935M18 ST50959907 845630-49-1 MolPort-002-611-546 N~3~-cyclopentyl-1-(4-fluorobenzyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide MCULE-1768862380 STK904741 N-cyclopentyl-1-(4-fluorobenzyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide CHEMBL1483092 SMR000647253 [ Show all ]
Inchi Key	AAOGXTPEJATQRN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H24FN5O2/c1-15-5-4-12-30-22(15)29-23-20(25(30)33)13-19(24(32)28-18-6-2-3-7-18)21(27)31(23)14-16-8-10-17(26)11-9-16/h4-5,8-13,18,27H,2-3,6-7,14H2,1H3,(H,28,32)
PubChem CID	3461011
ChEMBL	CHEMBL1483092
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
387	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463004	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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