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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001072616
Molecular formula	C24H25N3O3
IUPAC name	methyl 4-[[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]carbamoyl]benzoate
Molecular weight	403.482
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.1
Synonyms	4-[[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]carbamoyl]benzoic acid methyl ester methyl 4-({[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydro-1H-indazol-4-yl]amino}carbonyl)benzoate MolPort-005-093-591 HMS2967K12 4-[[[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]amino]-oxomethyl]benzoic acid methyl ester methyl 4-[[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]carbamoyl]benzoate CHEMBL1601295 SMR000658589 MCULE-9977911037 BDBM91030 cid_24793406 [ Show all ]
Inchi Key	AAFPEBOTHTYVHR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25N3O3/c1-15-7-12-19(13-16(15)2)27-22-6-4-5-21(20(22)14-25-27)26-23(28)17-8-10-18(11-9-17)24(29)30-3/h7-14,21H,4-6H2,1-3H3,(H,26,28)
PubChem CID	24793406
ChEMBL	CHEMBL1601295
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
180	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
462987	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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