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BioLiP
Download all results in tab-seperated text for 713946 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    14801 1haz:B (1.4) BS01 peptide 3.4.21.36 GO:0004252 ... P00772 11473259
    14802 1haz:B (1.4) BS02 CA 3.4.21.36 GO:0004252 ... P00772 11473259
    14803 1hb0:B (2.05) BS01 CA 3.4.21.36 GO:0004252 ... P00772 11473259
    14804 1hb1:A (1.55) BS01 OCV 1.21.3.1 GO:0005506 ... P05326 11755401
    14805 1hb1:A (1.55) BS02 FE2 1.21.3.1 GO:0005506 ... P05326 11755401
    14806 1hb2:A (1.3) BS01 SCV 1.21.3.1 GO:0005506 ... P05326 11755401
    14807 1hb2:A (1.3) BS02 FE2 1.21.3.1 GO:0005506 ... P05326 11755401
    14808 1hb3:A (1.4) BS01 SCV 1.21.3.1 GO:0005506 ... P05326 11755401
    14809 1hb3:A (1.4) BS02 FE2 1.21.3.1 GO:0005506 ... P05326 11755401
    14810 1hb4:A (1.5) BS01 SCV 1.21.3.1 GO:0005506 ... P05326 11755401
    14811 1hb4:A (1.5) BS02 FE2 1.21.3.1 GO:0005506 ... P05326 11755401
    14812 1hba:A (2.1) BS01 HEM ? GO:0004601 ... P69905 1567857
    14813 1hba:B (2.1) BS01 HEM ? GO:0004601 ... P68871 1567857
    14814 1hba:C (2.1) BS01 HEM ? GO:0004601 ... P69905 1567857
    14815 1hba:D (2.1) BS01 HEM ? GO:0004601 ... P68871 1567857
    14816 1hbb:A (1.9) BS01 HEM ? GO:0004601 ... P69905 1567857
    14817 1hbb:B (1.9) BS01 HEM ? GO:0004601 ... P68871 1567857
    14818 1hbb:C (1.9) BS01 HEM ? GO:0004601 ... P69905 1567857
    14819 1hbb:D (1.9) BS01 HEM ? GO:0004601 ... P68871 1567857
    14820 1hbg:A (1.5) BS01 HEM ? GO:0001666 ... P02216 2585515
    14821 1hbh:A (2.2) BS01 HEM ? GO:0004601 ... P80043 7623382
    14822 1hbh:B (2.2) BS01 HEM ? GO:0004601 ... P80044 7623382
    14823 1hbh:C (2.2) BS01 HEM ? GO:0004601 ... P80043 7623382
    14824 1hbh:D (2.2) BS01 HEM ? GO:0004601 ... P80044 7623382
    14825 1hbi:A (1.7) BS01 HEM ? GO:0001666 ... P02213 7929217
    14826 1hbi:A (1.7) BS02 OXY ? GO:0001666 ... P02213 7929217
    14827 1hbi:A (1.7) BS03 HEM ? GO:0001666 ... P02213 7929217
    14828 1hbi:B (1.7) BS01 HEM ? GO:0001666 ... P02213 7929217
    14829 1hbi:B (1.7) BS02 HEM ? GO:0001666 ... P02213 7929217
    14830 1hbi:B (1.7) BS03 OXY ? GO:0001666 ... P02213 7929217
    14831 1hbj:A (2.5) BS01 FBQ 3.1.1.7 GO:0001507 ... P04058 11563919 PDBbind: -logKd/Ki=8.52, IC50=3.0nM
    BindingDB: IC50=11000nM
    14832 1hbk:A (2.0) BS01 COA ? GO:0000062 ... Q8IK57 11491287
    14833 1hbm:A (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14834 1hbm:A (1.8) BS02 SHT 2.8.4.1 GO:0005737 ... P11558 11491299
    14835 1hbm:A (1.8) BS03 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14836 1hbm:A (1.8) BS04 SHT 2.8.4.1 GO:0005737 ... P11558 11491299
    14837 1hbm:B (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    14838 1hbm:B (1.8) BS02 SHT 2.8.4.1 GO:0005737 ... P11560 11491299
    14839 1hbm:C (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    14840 1hbm:D (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14841 1hbm:D (1.8) BS02 SHT 2.8.4.1 GO:0005737 ... P11558 11491299
    14842 1hbm:D (1.8) BS03 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14843 1hbm:D (1.8) BS04 SHT 2.8.4.1 GO:0005737 ... P11558 11491299
    14844 1hbm:E (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    14845 1hbm:E (1.8) BS02 SHT 2.8.4.1 GO:0005737 ... P11560 11491299
    14846 1hbm:F (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    14847 1hbn:A (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14848 1hbn:A (1.16) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14849 1hbn:A (1.16) BS03 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    14850 1hbn:A (1.16) BS04 MG 2.8.4.1 GO:0005737 ... P11558 11491299
    14851 1hbn:A (1.16) BS05 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14852 1hbn:A (1.16) BS06 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14853 1hbn:B (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    14854 1hbn:B (1.16) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    14855 1hbn:B (1.16) BS03 COM 2.8.4.1 GO:0005737 ... P11560 11491299
    14856 1hbn:C (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    14857 1hbn:D (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14858 1hbn:D (1.16) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14859 1hbn:D (1.16) BS03 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14860 1hbn:D (1.16) BS04 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14861 1hbn:D (1.16) BS05 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    14862 1hbn:E (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    14863 1hbn:E (1.16) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    14864 1hbn:E (1.16) BS03 COM 2.8.4.1 GO:0005737 ... P11560 11491299
    14865 1hbn:F (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    14866 1hbn:F (1.16) BS02 MG 2.8.4.1 GO:0005737 ... P11562 11491299
    14867 1hbo:A (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14868 1hbo:A (1.78) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14869 1hbo:A (1.78) BS03 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    14870 1hbo:A (1.78) BS04 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14871 1hbo:A (1.78) BS05 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14872 1hbo:B (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    14873 1hbo:B (1.78) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    14874 1hbo:B (1.78) BS03 COM 2.8.4.1 GO:0005737 ... P11560 11491299
    14875 1hbo:C (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    14876 1hbo:D (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14877 1hbo:D (1.78) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14878 1hbo:D (1.78) BS03 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14879 1hbo:D (1.78) BS04 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14880 1hbo:D (1.78) BS05 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    14881 1hbo:E (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    14882 1hbo:E (1.78) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    14883 1hbo:F (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    14884 1hbp:A (1.9) BS01 RTL ? GO:0005501 ... P18902 8496140
    14885 1hbr:A (2.3) BS01 HEM ? GO:0004601 ... P02001 10037733
    14886 1hbr:B (2.3) BS01 HEM ? GO:0004601 ... P02112 10037733
    14887 1hbr:C (2.3) BS01 HEM ? GO:0004601 ... P02001 10037733
    14888 1hbr:D (2.3) BS01 HEM ? GO:0004601 ... P02112 10037733
    14889 1hbs:A (3.0) BS01 HEM ? GO:0004601 ... P69905 4008491
    14890 1hbs:B (3.0) BS01 HEM ? GO:0004601 ... P68871 4008491
    14891 1hbs:C (3.0) BS01 HEM ? GO:0004601 ... P69905 4008491
    14892 1hbs:D (3.0) BS01 HEM ? GO:0004601 ... P68871 4008491
    14893 1hbs:E (3.0) BS01 HEM ? GO:0004601 ... P69905 4008491
    14894 1hbs:F (3.0) BS01 HEM ? GO:0004601 ... P68871 4008491
    14895 1hbs:G (3.0) BS01 HEM ? GO:0004601 ... P69905 4008491
    14896 1hbs:H (3.0) BS01 HEM ? GO:0004601 ... P68871 4008491
    14897 1hbt:H (2.0) BS01 peptide 3.4.21.5 GO:0004252 ... P00734 7547884
    14898 1hbt:H (2.0) BS02 peptide 3.4.21.5 GO:0004252 ... P00734 7547884
    14899 1hbu:A (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14900 1hbu:A (1.9) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14901 1hbu:A (1.9) BS03 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    14902 1hbu:A (1.9) BS04 MG 2.8.4.1 GO:0005737 ... P11558 11491299
    14903 1hbu:A (1.9) BS05 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14904 1hbu:A (1.9) BS06 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14905 1hbu:B (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    14906 1hbu:B (1.9) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    14907 1hbu:B (1.9) BS03 COM 2.8.4.1 GO:0005737 ... P11560 11491299
    14908 1hbu:C (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    14909 1hbu:D (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14910 1hbu:D (1.9) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14911 1hbu:D (1.9) BS03 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    14912 1hbu:D (1.9) BS04 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    14913 1hbu:D (1.9) BS05 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    14914 1hbu:E (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    14915 1hbu:E (1.9) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    14916 1hbu:E (1.9) BS03 COM 2.8.4.1 GO:0005737 ... P11560 11491299
    14917 1hbu:F (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    14918 1hbv:A (2.3) BS01 GAN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0004190 ... P03366 7650677 MOAD: Ki=430nM
    PDBbind: -logKd/Ki=6.37, Ki=430nM
    14919 1hbv:B (2.3) BS01 GAN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0004190 ... P03366 7650677 PDBbind: -logKd/Ki=6.37, Ki=430nM
    14920 1hbx:A (3.15) BS01 dna ? GO:0000981 ... P11831 11406578
    14921 1hbx:A (3.15) BS02 dna ? GO:0000981 ... P11831 11406578
    14922 1hbx:B (3.15) BS01 dna ? GO:0000981 ... P11831 11406578
    14923 1hbx:B (3.15) BS02 dna ? GO:0000981 ... P11831 11406578
    14924 1hbx:D (3.15) BS01 dna ? GO:0000981 ... P11831 11406578
    14925 1hbx:D (3.15) BS02 dna ? GO:0000981 ... P11831 11406578
    14926 1hbx:E (3.15) BS01 dna ? GO:0000981 ... P11831 11406578
    14927 1hbx:E (3.15) BS02 dna ? GO:0000981 ... P11831 11406578
    14928 1hbx:G (3.15) BS01 dna ? GO:0003700 ... P28324 11406578
    14929 1hbx:G (3.15) BS02 dna ? GO:0003700 ... P28324 11406578
    14930 1hbx:H (3.15) BS01 dna ? GO:0003700 ... P28324 11406578
    14931 1hbx:H (3.15) BS02 dna ? GO:0003700 ... P28324 11406578
    14932 1hby:A (2.0) BS01 PO4 3.1.27.- GO:0001525 ... P03950 11468363
    14933 1hbz:A (1.5) BS01 HEM 1.11.1.6 GO:0004096 ... P29422 1426241
    14934 1hc1:A (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    14935 1hc1:A (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    14936 1hc1:B (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    14937 1hc1:B (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    14938 1hc1:C (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    14939 1hc1:C (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    14940 1hc1:D (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    14941 1hc1:D (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    14942 1hc1:E (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    14943 1hc1:E (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    14944 1hc1:F (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    14945 1hc1:F (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    14946 1hc7:A (2.43) BS01 ZN 6.1.1.15 GO:0000166 ... Q5SM28 11399074
    14947 1hc7:B (2.43) BS01 ZN 6.1.1.15 GO:0000166 ... Q5SM28 11399074
    14948 1hc7:C (2.43) BS01 ZN 6.1.1.15 GO:0000166 ... Q5SM28 11399074
    14949 1hc7:D (2.43) BS01 ZN 6.1.1.15 GO:0000166 ... Q5SM28 11399074
    14950 1hc8:A (2.8) BS01 rna ? GO:0003735 ... P56210 12054794
    14951 1hc8:B (2.8) BS01 rna ? GO:0003735 ... P56210 12054794
    14952 1hc9:A (1.8) BS01 peptide ? GO:0005515 ... P60616 11683996
    14953 1hc9:B (1.8) BS01 peptide ? GO:0005515 ... P60615 11683996
    14954 1hca:A (2.3) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 N/A
    14955 1hcb:A (1.6) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0004064 ... P00915 8057362
    14956 1hcb:A (1.6) BS02 BCT 4.2.1.1
    4.2.1.69
    GO:0004064 ... P00915 8057362 BindingDB: Ki=12000000nM
    14957 1hch:A (1.57) BS01 HEM 1.11.1.7 GO:0004601 ... P00433 12024218
    14958 1hch:A (1.57) BS02 CA 1.11.1.7 GO:0004601 ... P00433 12024218
    14959 1hch:A (1.57) BS03 CA 1.11.1.7 GO:0004601 ... P00433 12024218
    14960 1hch:A (1.57) BS04 O 1.11.1.7 GO:0004601 ... P00433 12024218
    14961 1hck:A (1.9) BS01 MG 2.7.11.22 GO:0000082 ... P24941 8917641
    14962 1hck:A (1.9) BS02 ATP 2.7.11.22 GO:0000082 ... P24941 8917641
    14963 1hco:A (2.7) BS01 HEM ? GO:0004601 ... P69905 7373648
    14964 1hco:B (2.7) BS01 HEM ? GO:0004601 ... P68871 7373648
    14965 1hcp:A (-1.00) BS01 ZN ? GO:0003700 ... P03372 16100953
    14966 1hcp:A (-1.00) BS02 ZN ? GO:0003700 ... P03372 16100953
    14967 1hcq:A (2.4) BS01 dna ? GO:0003700 ... P03372 8221895
    14968 1hcq:A (2.4) BS02 dna ? GO:0003700 ... P03372 8221895
    14969 1hcq:A (2.4) BS03 ZN ? GO:0003700 ... P03372 8221895
    14970 1hcq:A (2.4) BS04 ZN ? GO:0003700 ... P03372 8221895
    14971 1hcq:B (2.4) BS01 dna ? GO:0003700 ... P03372 8221895
    14972 1hcq:B (2.4) BS02 dna ? GO:0003700 ... P03372 8221895
    14973 1hcq:B (2.4) BS03 ZN ? GO:0003700 ... P03372 8221895
    14974 1hcq:B (2.4) BS04 ZN ? GO:0003700 ... P03372 8221895
    14975 1hcq:E (2.4) BS01 dna ? GO:0003700 ... P03372 8221895
    14976 1hcq:E (2.4) BS02 dna ? GO:0003700 ... P03372 8221895
    14977 1hcq:E (2.4) BS03 ZN ? GO:0003700 ... P03372 8221895
    14978 1hcq:E (2.4) BS04 ZN ? GO:0003700 ... P03372 8221895
    14979 1hcq:F (2.4) BS01 dna ? GO:0003700 ... P03372 8221895
    14980 1hcq:F (2.4) BS02 dna ? GO:0003700 ... P03372 8221895
    14981 1hcq:F (2.4) BS03 ZN ? GO:0003700 ... P03372 8221895
    14982 1hcq:F (2.4) BS04 ZN ? GO:0003700 ... P03372 8221895
    14983 1hcr:A (2.3) BS01 dna ? GO:0000150 ... P03013 8278807
    14984 1hcr:A (2.3) BS02 dna ? GO:0000150 ... P03013 8278807
    14985 1hcy:A (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    14986 1hcy:A (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    14987 1hcz:A (1.96) BS01 HEM ? GO:0005506 ... P36438 8762139
    14988 1hda:A (2.2) BS01 HEM ? GO:0004601 ... P01966 8411160
    14989 1hda:B (2.2) BS01 HEM ? GO:0004601 ... P02070 8411160
    14990 1hda:C (2.2) BS01 HEM ? GO:0004601 ... P01966 8411160
    14991 1hda:D (2.2) BS01 HEM ? GO:0004601 ... P02070 8411160
    14992 1hdb:A (2.2) BS01 HEM ? GO:0004601 ... P69905 8639677
    14993 1hdb:B (2.2) BS01 HEM ? GO:0004601 ... P68871 8639677
    14994 1hdb:C (2.2) BS01 HEM ? GO:0004601 ... P69905 8639677
    14995 1hdb:D (2.2) BS01 HEM ? GO:0004601 ... P68871 8639677
    14996 1hdc:A (2.2) BS01 CBO 1.1.1.53 GO:0008202 ... P19992 7866748 MOAD: Ki=1uM
    14997 1hdc:B (2.2) BS01 CBO 1.1.1.53 GO:0008202 ... P19992 7866748 MOAD: Ki=1uM
    14998 1hdc:C (2.2) BS01 CBO 1.1.1.53 GO:0008202 ... P19992 7866748 MOAD: Ki=1uM
    14999 1hdc:D (2.2) BS01 CBO 1.1.1.53 GO:0008202 ... P19992 7866748 MOAD: Ki=1uM
    15000 1hdd:C (2.8) BS01 dna ? GO:0000981 ... P02836 1977522

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218