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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	HOMATROPINE
Molecular formula	C16H21NO3
IUPAC name	(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate
Molecular weight	275.348
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.9
Synonyms	DL-Mandelsaeure-tropylester Lopac0_000592 NCGC00015489-02 SBB057543 (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-acetate 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate BDBM82370 CAS_87-00-3 Mandelyltropeine NCI60_004650 STK693930 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, mandelate (ester) AC1L1GCH CTK8D8671 Homotropine Methylhomatropinum NSC_5821 Tropinmandelsaeureester 3alpha-Tropylmandelat alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]octan-3-yl ester EINECS 201-716-8 LS-158015 NCGC00015489-03 SCHEMBL23970 (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate # Benzeneacetic acid, .alpha.-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-(.+/-.)- CCG-204681 Homatropine [BAN] Mandelytropeine NSC-60600 Tropine, mandelate 1.alpha.H,5.alpha.H-Tropan-3-.alpha.-ol, mandelate AC1Q625F DL-Homatropine hydrobromide L000927 MolPort-001-779-641 Omatropina [DCIT] ZTVIKZXZYLEVOL-UHFFFAOYSA-N (.+/-.)-Homatropine 8-methyl-8-azabicyclo[3.2.1]oct-3-yl 2-hydroxy-2-phenylacetate AN-15060 Homatropin Mandelic acid, 3d-tropanyl ester NCGC00162198-01 SR-01000075900-6 (RS)-3alpha(1alphaH,5alphaH)-Tropanylmandelat BRN 0087959 CHEMBL1237117 Homoatropine MCULE-7109134658 NSC60600 Tropine, mandelate (ester) 3.alpha.-Hydroxy-1.alpha.H,5.alpha.H-tropanium mandelate (ester) AKOS005605558 [ Show all ]
Inchi Key	ZTVIKZXZYLEVOL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3
PubChem CID	3623
ChEMBL	N/A
IUPHAR	N/A
BindingDB	82370
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
437279	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
437278	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
437277	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
437276	Muscarinic acetylcholine receptor M4	P17200	CHRM4	Gallus gallus (Chicken)	490

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