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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	GUANOSINE TRIPHOSPHATE
Molecular formula	C10H16N5O14P3
IUPAC name	[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Molecular weight	523.18
Hydrogen bond acceptor	16
Hydrogen bond donor	8
XlogP	-5.7
Synonyms	XKMLYUALXHKNFT-UUOKFMHZSA-N 6H-purin-6-one, 2-amino-1,9-dihydro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-beta-D-ribofuranosyl]- C00044 GTP Guanosine 5a(2)-triphosphate sodium salt hydrate Guanosine5'-(tetrahydrogen triphosphate), sodium salt (1:2) [3h]guanosine triphosphate 1jlr 9-\|A-D-ribofuranosylguanine-5'-triphosphate CTK5A4465 Guanosine 5'-(tetrahydrogen triphosphate) LS-73963 ({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid 56001-37-7 AKOS030527437 DTXSID30235328 Guanosine 5'-triphosphorate guanosine-5'-(tetrahydrogentriphosphate) SCHEMBL44408 ZINC60094177 1e96 86-01-1 CHEBI:15996 GTP 100mM Solution (Guanosine-5'-triphosphate, trisodium salt) Guanosine 5_-triphosphate guanosintriphosphat [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate 36051-31-7 AC1L1NEA D0EQ4T guanosine 5'-triphosphate Guanosine triphosphate (6Cl) NCGC00163327-01 01WV7J708X 6A1C76E9-BEFB-4684-B0C1-8C50AE53C506 BRN 1201437 EINECS 201-647-3 Guanosine 5'-triphosphoric acid Guanosine-5'-triphosphate UNII-01WV7J708X [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate 1j2j 9-\|A-D-ribofuranosyl-2-amino-6-oxo-purine-5'-triphosphate CHEMBL1233147 GTPL1742 Guanosine mono(tetrahydrogen triphosphate) (ester) H4gtp [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate 5'-GTP AC1Q1IDH DB04137 Guanosine 5'-triphosphate Disodium Guanosine, mono(tetrahydrogen triphosphate) (ester) SCHEMBL15900104 [ Show all ]
Inchi Key	XKMLYUALXHKNFT-UUOKFMHZSA-N
Inchi ID	InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
PubChem CID	135398633
ChEMBL	N/A
IUPHAR	1742
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555254	P2Y purinoceptor 4	P51582	P2RY4	Homo sapiens (Human)	365
555255	P2Y purinoceptor 4	O35811	P2ry4	Rattus norvegicus (Rat)	361

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