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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	P2Y purinoceptor 4
Species	Rattus norvegicus (Rat)
Gene	P2ry4
Synonym	UNR pyrimidinoceptor pyrimidinergic receptor P2Y P2Y4R P2Y4 receptor P2Y4 P2Y purinoceptor 4 P2Y ATP receptor 4 NRU uridine nucleotide receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	361
Amino acid sequence	MTSAESLLFTSLGPSPSSGDGDCRFNEEFKFILLPMSYAVVFVLGLALNAPTLWLFLFRLRPWDATATYMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGLCKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRAIRWGRPRFASLLCLGVWLVVAGCLVPNLFFVTTNANGTTILCHDTTLPEEFDHYVYFSSAVMVLLFGLPFLITLVCYGLMARRLYRPLPGAGQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYQARLLQADCHVLNIVNVVYKVTRPLASANSCLDPVLYLFTGDKYRNQLQQLCRGSKPKPRTAASSLALVTLHEESISRWADTHQDSTFSAYEGDRL
UniProt	O35811
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2124
IUPHAR	325
DrugBank	N/A

Ligand

Name	GUANOSINE TRIPHOSPHATE
Molecular formula	C10H16N5O14P3
IUPAC name	[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Molecular weight	523.18
Hydrogen bond acceptor	16
Hydrogen bond donor	8
XlogP	-5.7
Synonyms	Guanosine 5a(2)-triphosphate sodium salt hydrate Guanosine5'-(tetrahydrogen triphosphate), sodium salt (1:2) XKMLYUALXHKNFT-UUOKFMHZSA-N 6H-purin-6-one, 2-amino-1,9-dihydro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-beta-D-ribofuranosyl]- C00044 GTP LS-73963 [3h]guanosine triphosphate 1jlr 9-\|A-D-ribofuranosylguanine-5'-triphosphate CTK5A4465 Guanosine 5'-(tetrahydrogen triphosphate) Guanosine 5'-triphosphorate guanosine-5'-(tetrahydrogentriphosphate) SCHEMBL44408 ({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid 56001-37-7 AKOS030527437 DTXSID30235328 Guanosine 5_-triphosphate guanosintriphosphat ZINC60094177 1e96 86-01-1 CHEBI:15996 GTP 100mM Solution (Guanosine-5'-triphosphate, trisodium salt) Guanosine triphosphate (6Cl) NCGC00163327-01 [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate 36051-31-7 AC1L1NEA D0EQ4T guanosine 5'-triphosphate Guanosine 5'-triphosphoric acid Guanosine-5'-triphosphate UNII-01WV7J708X 01WV7J708X 6A1C76E9-BEFB-4684-B0C1-8C50AE53C506 BRN 1201437 EINECS 201-647-3 Guanosine mono(tetrahydrogen triphosphate) (ester) H4gtp [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate 1j2j 9-\|A-D-ribofuranosyl-2-amino-6-oxo-purine-5'-triphosphate CHEMBL1233147 GTPL1742 Guanosine, mono(tetrahydrogen triphosphate) (ester) SCHEMBL15900104 [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate 5'-GTP AC1Q1IDH DB04137 Guanosine 5'-triphosphate Disodium [ Show all ]
Inchi Key	XKMLYUALXHKNFT-UUOKFMHZSA-N
Inchi ID	InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
PubChem CID	135398633
ChEMBL	N/A
IUPHAR	1742
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	2511.89 nM	PMID10779375	IUPHAR

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