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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	esoxybutynin
Molecular formula	C22H31NO3
IUPAC name	4-(diethylamino)but-2-ynyl (2R)-2-cyclohexyl-2-hydroxy-2-phenylacetate
Molecular weight	357.494
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.2
Synonyms	XIQVNETUBQGFHX-QFIPXVFZSA-N (2R)-2-cyclohexyl-2-hydroxy-2-phenylacetic acid 4-(diethylamino)but-2-ynyl ester AC1O1JMH esoxibutinina esoxybutyninum 4-(diethylamino)but-2-ynyl (2R)-2-cyclohexyl-2-hydroxy-2-phenylacetate BDBM50151858 UNII-5BRQ29UUB7 5BRQ29UUB7 CHEBI:51329 ZINC1530752 (r)-oxybutynin AJ-26689 Oxybutynin, (-)- 4-(diethylamino)but-2-ynyl (2R)-2-cyclohexyl-2-oxidanyl-2-phenyl-ethanoate Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(diethylamino)-2-butyn-1-yl ester, (alphaR)- UNII-K9P6MC7092 component XIQVNETUBQGFHX-QFIPXVFZSA-N (-)-Oxybutynin A831004 CHEMBL185434 4-(diethylamino)but-2-yn-1-yl (2S)-cyclohexyl(hydroxy)phenylacetate AKOS027378211 esoxybutynine SCHEMBL25880 BIDD:GT0624 [ Show all ]
Inchi Key	XIQVNETUBQGFHX-QFIPXVFZSA-N
Inchi ID	InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3/t22-/m0/s1
PubChem CID	6098167
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50151858
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
392827	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
392826	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
392824	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
392825	Muscarinic acetylcholine receptor M4	P17200	CHRM4	Gallus gallus (Chicken)	490

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