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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1651823
Molecular formula	C63H68N14O6S2
IUPAC name	4-[3-[[2-[[1-[2-[2-[4-[[4-[(4R)-1-acetyl-2,2,4-trimethyl-6-[(4-phenylbenzoyl)amino]-3H-quinolin-4-yl]phenoxy]methyl]triazol-1-yl]ethoxy]ethyl]triazol-4-yl]methylamino]-2-oxoethyl]amino]phenyl]-5-amino-N-tert-butyl-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
Molecular weight	1181.45
Hydrogen bond acceptor	16
Hydrogen bond donor	5
XlogP	8.7
Synonyms	(R)-4-(3-(2-((1-(2-(2-(4-((4-(1-acetyl-6-biphenyl-4-ylcarboxamido-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-4-yl)phenoxy)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methylamino)-2-oxoethylamino)phenyl)-5-amino-N-tert-butyl-2-(methyl BDBM50335469
Inchi Key	VHJQLOSXJQIMCD-AFLCPGBUSA-N
Inchi ID	InChI=1S/C63H68N14O6S2/c1-39(78)77-51-26-23-46(67-57(80)42-19-17-41(18-20-42)40-13-10-9-11-14-40)32-50(51)63(7,38-62(77,5)6)44-21-24-49(25-22-44)83-37-48-36-76(74-72-48)28-30-82-29-27-75-35-47(71-73-75)33-66-52(79)34-65-45-16-12-15-43(31-45)55-53-54(64)56(58(81)70-61(2,3)4)85-59(53)69-60(68-55)84-8/h9-26,31-32,35-36,65H,27-30,33-34,37-38,64H2,1-8H3,(H,66,79)(H,67,80)(H,70,81)/t63-/m1/s1
PubChem CID	53323417
ChEMBL	CHEMBL1651823
IUPHAR	N/A
BindingDB	50335469
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
355266	Follicle-stimulating hormone receptor	P23945	FSHR	Homo sapiens (Human)	695
355265	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699

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