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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2315923
Molecular formula	C23H25F3N6O2S
IUPAC name	N-[1-[4-hydroxy-4-(1,2-thiazol-5-yl)cyclohexyl]azetidin-3-yl]-2-[[6-(trifluoromethyl)quinazolin-4-yl]amino]acetamide
Molecular weight	506.548
Hydrogen bond acceptor	11
Hydrogen bond donor	3
XlogP	3.0
Synonyms	N-(1-(4-hydroxy-4-(isothiazol-5-yl)cyclohexyl)azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide BDBM163453 US9062048, 81 SCHEMBL9998569 BDBM50425704 CHEMBL3704097 UAISHSJUKZZNTF-UHFFFAOYSA-N [ Show all ]
Inchi Key	UAISHSJUKZZNTF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25F3N6O2S/c24-23(25,26)14-1-2-18-17(9-14)21(29-13-28-18)27-10-20(33)31-15-11-32(12-15)16-3-6-22(34,7-4-16)19-5-8-30-35-19/h1-2,5,8-9,13,15-16,34H,3-4,6-7,10-12H2,(H,31,33)(H,27,28,29)
PubChem CID	68003782
ChEMBL	CHEMBL3704097
IUPHAR	N/A
BindingDB	163453
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
462092	C-C chemokine receptor-like 2	O00421	CCRL2	Homo sapiens (Human)	344

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