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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL402769
Molecular formula	C32H41ClF3N3O2
IUPAC name	N-[(1S)-1-[2-[1-[(3R,4S)-1-tert-butyl-4-[4-(trifluoromethyl)phenyl]pyrrolidine-3-carbonyl]piperidin-4-yl]-5-chlorophenyl]propyl]acetamide
Molecular weight	592.144
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	6.0
Synonyms	BDBM50373474
Inchi Key	PNFDTYPRKXTXAO-ULNSLHSMSA-N
Inchi ID	InChI=1S/C32H41ClF3N3O2/c1-6-29(37-20(2)40)26-17-24(33)11-12-25(26)22-13-15-38(16-14-22)30(41)28-19-39(31(3,4)5)18-27(28)21-7-9-23(10-8-21)32(34,35)36/h7-12,17,22,27-29H,6,13-16,18-19H2,1-5H3,(H,37,40)/t27-,28+,29+/m1/s1
PubChem CID	24857886
ChEMBL	CHEMBL402769
IUPHAR	N/A
BindingDB	50373474
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
263938	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
263936	Melanocortin receptor 4	P70596	Mc4r	Rattus norvegicus (Rat)	332
263937	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
263939	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325

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