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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Pyrazolone, 1
Molecular formula	C20H21ClN4O2
IUPAC name	1-(4-chlorophenyl)-3-(1-methyl-3-oxo-2-phenyl-5-propan-2-ylpyrazol-4-yl)urea
Molecular weight	384.864
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.1
Synonyms	compound 43 [PMID:16697190] AS-55050 D0WB8E TC-FPR 43 1-(4-Chlorophenyl)-3-(5-isopropyl-1-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea N-(4-Chlorophenyl)-N-[2,3-dihydro-1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-1H-pyrazol-4-yl]-urea 903895-98-7 compound 43 [PMID:23160941] SCHEMBL18894545 BDBM21692 GTPL5831 UNII-T77D5438IM 1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(propan-2-yl)-2,3-dihydro-1H-pyrazol-4-yl]urea CHEMBL379761 NCGC00387180-01 3-(4-chlorophenyl)-1-(1-methyl-3-oxo-2-phenyl-5-propan-2-ylpyrazol-4-yl)urea AKOS025142013 Cpd43 T77D5438IM CHEMBL-379761 MolPort-035-941-175 ZINC14976923 1-(4-chlorophenyl)-3-[1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl]urea [ Show all ]
Inchi Key	PAEBEUZTAPIOIO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H21ClN4O2/c1-13(2)18-17(23-20(27)22-15-11-9-14(21)10-12-15)19(26)25(24(18)3)16-7-5-4-6-8-16/h4-13H,1-3H3,(H2,22,23,27)
PubChem CID	24776341
ChEMBL	CHEMBL379761
IUPHAR	5831
BindingDB	21692
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554529	fMet-Leu-Phe receptor	P33766	Fpr1	Mus musculus (Mouse)	364
554528	Formyl peptide receptor 2	O88536	Fpr2	Mus musculus (Mouse)	351
254639	N-formyl peptide receptor 2	P25090	FPR2	Homo sapiens (Human)	351

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