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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL215958
Molecular formula	C30H33N3O3
IUPAC name	4-(3,4-dimethylphenoxy)-3-[[(E)-3-phenylprop-2-enoyl]amino]-N-(2-pyrrolidin-1-ylethyl)benzamide
Molecular weight	483.612
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.2
Synonyms	BDBM50192527 SCHEMBL6373069 3-cinnamamido-4-(3,4-dimethylphenoxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Inchi Key	NERZZHAUEVWREN-RVDMUPIBSA-N
Inchi ID	InChI=1S/C30H33N3O3/c1-22-10-13-26(20-23(22)2)36-28-14-12-25(30(35)31-16-19-33-17-6-7-18-33)21-27(28)32-29(34)15-11-24-8-4-3-5-9-24/h3-5,8-15,20-21H,6-7,16-19H2,1-2H3,(H,31,35)(H,32,34)/b15-11+
PubChem CID	11620005
ChEMBL	CHEMBL215958
IUPHAR	N/A
BindingDB	50192527
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
221473	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353
221474	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
221475	Melanin-concentrating hormone receptor 1	Q8JZL2	Mchr1	Mus musculus (Mouse)	353

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