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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL10079
Molecular formula	C25H22N2O
IUPAC name	2-phenyl-N-[(1R)-1-phenylpropyl]quinoline-4-carboxamide
Molecular weight	366.464
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.6
Synonyms	SCHEMBL6447531 2-phenyl-N-[(1R)-1-phenylpropyl]quinoline-4-carboxamide AC1LWX4B ZINC2105298 2-Phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide BDBM50074773 N-[(R)-alpha-Ethylbenzyl]-2-phenylquinoline-4-carboxamide [ Show all ]
Inchi Key	MXNGYQJJYRVGGJ-JOCHJYFZSA-N
Inchi ID	InChI=1S/C25H22N2O/c1-2-22(18-11-5-3-6-12-18)27-25(28)21-17-24(19-13-7-4-8-14-19)26-23-16-10-9-15-20(21)23/h3-17,22H,2H2,1H3,(H,27,28)/t22-/m1/s1
PubChem CID	1760287
ChEMBL	CHEMBL10079
IUPHAR	N/A
BindingDB	50074773
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
216649	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465
216652	Neuromedin-K receptor	P16177	Tacr3	Rattus norvegicus (Rat)	452
216650	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
216651	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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