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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3885379
Molecular formula	C21H19ClF3N3O
IUPAC name	7-[[(1S,2S)-2-(4-chlorophenyl)cyclopropyl]methoxy]-3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
Molecular weight	421.848
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	6.2
Synonyms	BDBM50209103 SCHEMBL16591448
Inchi Key	LETPPZNSGLCXSE-GDBMZVCRSA-N
Inchi ID	InChI=1S/C21H19ClF3N3O/c22-15-5-3-13(4-6-15)16-10-14(16)11-29-17-7-8-28-18(9-12-1-2-12)26-27-20(28)19(17)21(23,24)25/h3-8,12,14,16H,1-2,9-11H2/t14-,16-/m1/s1
PubChem CID	117972250
ChEMBL	CHEMBL3885379
IUPHAR	N/A
BindingDB	50209103
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
540732	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
540733	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879

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