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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL88664
Molecular formula	C21H29N5O2
IUPAC name	2-[3-[4-(2-hydroxyphenyl)piperazin-1-yl]propylamino]-N,N-dimethylpyridine-3-carboxamide
Molecular weight	383.496
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.8
Synonyms	SCHEMBL9027132 2-{3-[4-(2-hydroxyphenyl)-piperazin-1-yl]propylamino}-N,N-dimethylnicotinamide KWUUDOTZWFVZLU-UHFFFAOYSA-N
Inchi Key	KWUUDOTZWFVZLU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H29N5O2/c1-24(2)21(28)17-7-5-10-22-20(17)23-11-6-12-25-13-15-26(16-14-25)18-8-3-4-9-19(18)27/h3-5,7-10,27H,6,11-16H2,1-2H3,(H,22,23)
PubChem CID	10643699
ChEMBL	CHEMBL88664
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
180194	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
180193	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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