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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL419684
Molecular formula	C26H29ClN2O2
IUPAC name	(R)-[2-(4-chlorophenyl)-6-methoxyquinolin-4-yl]-(5-ethyl-1-azabicyclo[2.2.2]octan-2-yl)methanol
Molecular weight	436.98
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.4
Synonyms	(R)-[2-(4-Chloro-phenyl)-6-methoxy-quinolin-4-yl]-(5-ethyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol BDBM50290549
Inchi Key	KRRYXVSHQZNKGR-ICSOZYFDSA-N
Inchi ID	InChI=1S/C26H29ClN2O2/c1-3-16-15-29-11-10-18(16)12-25(29)26(30)22-14-24(17-4-6-19(27)7-5-17)28-23-9-8-20(31-2)13-21(22)23/h4-9,13-14,16,18,25-26,30H,3,10-12,15H2,1-2H3/t16?,18?,25?,26-/m1/s1
PubChem CID	10433192
ChEMBL	CHEMBL419684
IUPHAR	N/A
BindingDB	50290549
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
176626	Calcitonin gene-related peptide type 1 receptor	Q16602	CALCRL	Homo sapiens (Human)	461
176627	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
176628	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427
176630	G-protein coupled receptor 182	O15218	GPR182	Homo sapiens (Human)	404
176629	Type-1A angiotensin II receptor	P25095	Agtr1	Rattus norvegicus (Rat)	359

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