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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3354803
Molecular formula	C25H19F4N5O3
IUPAC name	methyl (3S)-11-carbamoyl-3-[(3-fluorophenyl)methyl]-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate
Molecular weight	513.453
Hydrogen bond acceptor	10
Hydrogen bond donor	2
XlogP	3.0
Synonyms	BDBM50036670
Inchi Key	KLOXHHJOPZIHOE-DEOSSOPVSA-N
Inchi ID	InChI=1S/C25H19F4N5O3/c1-37-23(36)24(10-13-3-2-4-17(26)9-13)20-15(12-32-24)11-31-22-18(19(21(30)35)33-34(20)22)14-5-7-16(8-6-14)25(27,28)29/h2-9,11,32H,10,12H2,1H3,(H2,30,35)/t24-/m0/s1
PubChem CID	118720430
ChEMBL	CHEMBL3354803
IUPHAR	N/A
BindingDB	50036670
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
448444	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
448445	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335

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