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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL124501
Molecular formula	C15H19NO4
IUPAC name	(1S,2S)-2-[(1R)-1-amino-1-carboxy-3-(3-methylphenyl)propyl]cyclopropane-1-carboxylic acid
Molecular weight	277.32
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-0.9
Synonyms	(1S,2S)-2-((R)-1-Amino-1-carboxy-3-m-tolyl-propyl)-cyclopropanecarboxylic acid BDBM50062520 SCHEMBL8491369 (alphaR,1S,2S)-alpha-Amino-alpha-(3-methylphenethyl)-2beta-carboxycyclopropane-1alpha-acetic acid
Inchi Key	KBDQFKQTJBFOTK-SLEUVZQESA-N
Inchi ID	InChI=1S/C15H19NO4/c1-9-3-2-4-10(7-9)5-6-15(16,14(19)20)12-8-11(12)13(17)18/h2-4,7,11-12H,5-6,8,16H2,1H3,(H,17,18)(H,19,20)/t11-,12-,15+/m0/s1
PubChem CID	10492773
ChEMBL	CHEMBL124501
IUPHAR	N/A
BindingDB	50062520
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
164945	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
164944	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879

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