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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL219162
Molecular formula	C25H21N3O4
IUPAC name	methyl N-[(3-methoxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Molecular weight	427.46
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.8
Synonyms	BDBM50194575 methyl N-[(3-methoxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate compound 2g [PMID: 16950620] SCHEMBL3959275 JLSTVOPSMZBZSR-UHFFFAOYSA-N N''-(3-methoxy-2-phenyl-quinoline-4-carbonyl)-N-phenyl-hydrazinecarboxylic acid methyl ester D0W3XD Methyl 2-{[3-methyloxy-2-phenyl-4-quinolinyl]carbonyl}-1-phenylhydrazinecarboxylate N',2-diphenylquinoline-4-carbohydrazide GTPL2129 [ Show all ]
Inchi Key	JLSTVOPSMZBZSR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H21N3O4/c1-31-23-21(24(29)27-28(25(30)32-2)18-13-7-4-8-14-18)19-15-9-10-16-20(19)26-22(23)17-11-5-3-6-12-17/h3-16H,1-2H3,(H,27,29)
PubChem CID	16049828
ChEMBL	CHEMBL219162
IUPHAR	2129
BindingDB	50194575
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
153935	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465
153936	Neuromedin-K receptor	P16177	Tacr3	Rattus norvegicus (Rat)	452
153938	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
153937	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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