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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1778239
Molecular formula	C24H25FN4O4S
IUPAC name	(1S,5S)-8-(4-fluorophenyl)sulfonyl-3-[5-methyl-6-(2-methylpyridin-3-yl)oxypyrimidin-4-yl]oxy-8-azabicyclo[3.2.1]octane
Molecular weight	484.546
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	4.2
Synonyms	BDBM50344501 (1S,5S)-8-(4-fluorophenylsulfonyl)-3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyrimidin-4-yloxy)-8-azabicyclo[3.2.1]octane
Inchi Key	JKYHHGCQASLIAE-OALUTQOASA-N
Inchi ID	InChI=1S/C24H25FN4O4S/c1-15-23(27-14-28-24(15)33-22-4-3-11-26-16(22)2)32-20-12-18-7-8-19(13-20)29(18)34(30,31)21-9-5-17(25)6-10-21/h3-6,9-11,14,18-20H,7-8,12-13H2,1-2H3/t18-,19-/m0/s1
PubChem CID	54581708
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50344501
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
153456	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335
153457	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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