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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL199495
Molecular formula	C27H33FN2O2
IUPAC name	2-fluoro-6-[[(2R)-2-[(1R)-1-hydroxy-2-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]ethyl]pyrrolidin-1-yl]methyl]phenol
Molecular weight	436.571
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.8
Synonyms	BDBM50175365 2-fluoro-6-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)phenol
Inchi Key	JKMQBGLZDUBJJR-JWQCQUIFSA-N
Inchi ID	InChI=1S/C27H33FN2O2/c1-27(2,16-19-12-13-20-7-3-4-8-21(20)15-19)29-17-25(31)24-11-6-14-30(24)18-22-9-5-10-23(28)26(22)32/h3-5,7-10,12-13,15,24-25,29,31-32H,6,11,14,16-18H2,1-2H3/t24-,25-/m1/s1
PubChem CID	10094574
ChEMBL	CHEMBL199495
IUPHAR	N/A
BindingDB	50175365
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
153144	Extracellular calcium-sensing receptor	P48442	Casr	Rattus norvegicus (Rat)	1079
153145	Extracellular calcium-sensing receptor	P41180	CASR	Homo sapiens (Human)	1078

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