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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL342758
Molecular formula	C41H39Cl2N3O2S
IUPAC name	3-cyano-N-[(2S)-2-(3,4-dichlorophenyl)-4-[4-[2-[(S)-methylsulfinyl]phenyl]piperidin-1-yl]butyl]-N-methyl-2-phenylnaphthalene-1-carboxamide
Molecular weight	708.742
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	8.7
Synonyms	N/A
Inchi Key	JGLJNFCHLBYJNG-ZSFUNLSLSA-N
Inchi ID	InChI=1S/C41H39Cl2N3O2S/c1-45(41(47)40-35-14-7-6-12-31(35)24-33(26-44)39(40)29-10-4-3-5-11-29)27-32(30-16-17-36(42)37(43)25-30)20-23-46-21-18-28(19-22-46)34-13-8-9-15-38(34)49(2)48/h3-17,24-25,28,32H,18-23,27H2,1-2H3/t32-,49+/m1/s1
PubChem CID	11399838
ChEMBL	CHEMBL342758
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
150369	Substance-K receptor	P79218	TACR2	Oryctolagus cuniculus (Rabbit)	384
150368	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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