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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1778253
Molecular formula	C21H25FN4O4S
IUPAC name	(1R,3S,5R)-8-cyclopropylsulfonyl-6-fluoro-3-[5-methyl-6-(2-methylpyridin-3-yl)oxypyrimidin-4-yl]oxy-8-azabicyclo[3.2.1]octane
Molecular weight	448.513
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	3.1
Synonyms	(1R,3S,5R)-8-(cyclopropylsulfonyl)-6-fluoro-3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyrimidin-4-yloxy)-8-azabicyclo[3.2.1]octane BDBM50344515
Inchi Key	JEMAKXAATWANMD-HLVPYZJISA-N
Inchi ID	InChI=1S/C21H25FN4O4S/c1-12-20(24-11-25-21(12)30-19-4-3-7-23-13(19)2)29-15-8-14-9-17(22)18(10-15)26(14)31(27,28)16-5-6-16/h3-4,7,11,14-18H,5-6,8-10H2,1-2H3/t14-,15+,17?,18-/m1/s1
PubChem CID	54586563
ChEMBL	CHEMBL1778253
IUPHAR	N/A
BindingDB	50344515
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
148983	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335
148984	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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